美国精神医学学会 · Psychiatric News· Psychiatric News Alert·· 2026-09-03AI 评分38
基因变异与拉莫三嗪罕见致命过敏反应相关
Gene Variation Associated With Rare, Life-Threatening Reaction to Lamotrigine
内容导读
一项发表于《JAMA Psychiatry》的研究显示，一种特定基因变异会增加患者对情绪稳定药物拉莫三嗪发生罕见但危及生命的过敏反应的风险，但该信息未包含在目前市售的药物基因组学检测面板中。
正文 · 原文
One specific gene variation increases a patient’s risk of a rare but life-threatening hypersensitivity reaction to the mood-stabilizing drug lamotrigine—but that information is not included on current commercially available pharmacogenomic panels, according to a study published today in JAMA Psychiatry.
来源：美国精神医学学会 · Psychiatric News · alert.psychnews.org